The lipotropic "fat-melting" injection used in medical weight-loss clinics for decades — a blend of methionine, inositol, choline, and B12 that supports fat metabolism.
Lipo-C is a lipotropic injection blend of essential nutrients that support liver fat metabolism. The classic formulation is known as MIC: Methionine, Inositol, Choline. Most modern versions (including Lipo-C+) add vitamin B12 (cyanocobalamin or methylcobalamin) plus additional B vitamins and amino acids like L-carnitine.
It’s been used in weight-loss clinics since the 1970s. Unlike GLP-1 drugs, it doesn’t suppress appetite or directly drive weight loss — it supports the body’s ability to process and mobilize fat, especially in the liver. Best viewed as metabolic support during a caloric deficit.
Not FDA approved as a weight-loss drug (individual ingredients are approved). Not WADA prohibited. Available from compounding pharmacies and research suppliers.
Essential amino acid and methyl donor. Required for the liver to produce lecithin, which emulsifies and mobilizes fat for transport and burning.
A sugar alcohol that supports insulin signaling and serotonin synthesis. Plays a role in hepatic lipid handling and can improve fasting insulin.
Critical for VLDL synthesis and fat export from the liver. Choline deficiency causes hepatic steatosis (fatty liver). Lipo-C ensures adequate supply for fat export.
Cofactors for cellular energy metabolism. B12 specifically supports red blood cell formation, nerve health, and methylation reactions. Usually added in high dose.
Often added to premium Lipo-C formulations. Shuttles long-chain fatty acids into mitochondria for beta-oxidation (fat burning).
Lipo-C as a proprietary blend has limited RCT data, but its individual components are well-studied.
| Benefit | Evidence |
|---|---|
| Fat mobilization | Mechanistically supports hepatic fat export; works best during caloric deficit |
| Energy | B12 deficiency is common; correction restores energy levels |
| Liver support | Choline addresses NAFLD-related fat buildup |
| Mood / cognition | B vitamin support improves methylation and mood in deficient patients |
| Adjunct to GLP-1s | Many providers add Lipo-C to semaglutide / tirzepatide protocols for metabolic support during rapid weight loss |
Expect modest, gradual support — not dramatic weight loss on its own.
Build your protocol, log every dose, monitor your body's response, and get reminders so you never miss a dose.
Start Tracking FreeSome weight-loss clinics dose 1 mL 2–3× per week during active weight loss. Not necessarily more effective than weekly; individual response varies.
Lipo-C comes as a pre-mixed sterile injectable liquid in multi-dose vials. No reconstitution needed. Typical vial is 10 or 30 mL.
Standard strength is ready-to-inject. 1 mL = 1 full dose. Most insulin syringes (1 mL cap) work; larger 3 mL syringes are more comfortable for IM.
Use our free peptide calculator to figure out your reconstitution volume, draw amount, and syringe units.
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Start Tracking FreeDisclaimer: This guide is for educational and informational purposes only and is not intended as medical advice, diagnosis, or treatment. The compounds discussed are not FDA approved for human use. Always consult a qualified healthcare provider before starting any new supplement or peptide protocol. StackTrax does not sell peptides or supplements directly — purchase links go to third-party vendors. StackTrax is not responsible for the products, quality, or business practices of any third-party vendor. This page contains affiliate links — StackTrax may earn a commission on purchases at no extra cost to you.
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